Protein Info for BWI76_RS20010 in Klebsiella michiganensis M5al
Annotation: catalase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 79% identical to CATA_PROMI: Catalase (katA) from Proteus mirabilis
KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 88% identity to cko:CKO_00531)MetaCyc: 54% identical to catalase monomer (Homo sapiens)
Catalase. [EC: 1.11.1.21, 1.11.1.6]; 1.11.1.6 [EC: 1.11.1.21, 1.11.1.6]
Predicted SEED Role
"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)
MetaCyc Pathways
- reactive oxygen species degradation (4/4 steps found)
- ethanol degradation IV (3/3 steps found)
- superoxide radicals degradation (2/2 steps found)
- methanol oxidation to formaldehyde IV (1/2 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.11.1.6
Use Curated BLAST to search for 1.11.1.21 or 1.11.1.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B6T0 at UniProt or InterPro
Protein Sequence (482 amino acids)
>BWI76_RS20010 catalase (Klebsiella michiganensis M5al) MSKKGLTTGAGAPVVDNNNVVTAGPRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGA YGKLTVTHDITRYTRAKLFSEVGKTTDLFLRFSTVAGERGAADAERDIRGFSIKFYTEEG NWDLVGNNTPIFYLRDPLKFPDLNHVVKRDPRTNLRNPTWKWDFFSLLPETLHQLTIDFS DRGIPRSYRHMHGFGSHAFSFINAENERFWVKFHFKSQQGIANLMDDEAKRLVAEDRESS QRDLYESIERGDFPRWTFYVQIMPEAEASRVPYNPFDLTKIWPHGDYPLIEVGVLELNRN PDNYFAEVEQVAMNPANVVPGVGFSPDRMLQGRLFSYGDTQRYRLGVNHHQIPVNAPRCP FHNYHRDGAMRVDGNSGNGVTYEPNSFGVFQEQPDFSEPPLSLEGAAAHWDHREDSDYFS QPRRLFELLGEDEHQRMFQRIANDMRDIPEFIQQRQIGLFSEVHPDYGAGVAAALQALKH GE