Protein Info for BWI76_RS19915 in Klebsiella michiganensis M5al
Annotation: DNA-binding response regulator
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 98% identical to RCSB_SALTY: Transcriptional regulatory protein RcsB (rcsB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG orthology group: K07687, two-component system, NarL family, captular synthesis response regulator RcsB (inferred from 98% identity to eoh:ECO103_2693)Predicted SEED Role
"DNA-binding capsular synthesis response regulator RcsB"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B738 at UniProt or InterPro
Protein Sequence (216 amino acids)
>BWI76_RS19915 DNA-binding response regulator (Klebsiella michiganensis M5al) MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP GDKYGDGITLIKYIKRHFPDLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKAL AALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLRLFAEGFLVTEIAKKLNRSIK TISSQKKSAMMKLGVENDIALLNYLSSVSLSSTDKD