Protein Info for BWI76_RS19340 in Klebsiella michiganensis M5al
Annotation: xylulokinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 56% identical to XYLB_ECOLI: Xylulose kinase (xylB) from Escherichia coli (strain K12)
KEGG orthology group: K00854, xylulokinase [EC: 2.7.1.17] (inferred from 95% identity to kpe:KPK_1623)MetaCyc: 56% identical to xylulokinase (Escherichia coli K-12 substr. MG1655)
Xylulokinase. [EC: 2.7.1.17]; 2.7.1.- [EC: 2.7.1.17]
Predicted SEED Role
"Xylulose kinase (EC 2.7.1.17)" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization or Xylose utilization (EC 2.7.1.17)
MetaCyc Pathways
- superpathway of glucose and xylose degradation (17/17 steps found)
- D-arabinitol degradation I (2/2 steps found)
- D-xylose degradation I (2/2 steps found)
- xylitol degradation I (1/2 steps found)
- superpathway of pentose and pentitol degradation (21/42 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.17
Use Curated BLAST to search for 2.7.1.17
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B6E7 at UniProt or InterPro
Protein Sequence (487 amino acids)
>BWI76_RS19340 xylulokinase (Klebsiella michiganensis M5al) MYLGIDLGTSEVKALVIDENNEVIASHSAPLSIQRPHPHWSEQSPQSWWEATEYLMATLR EKCAQHWPAIKAIGLSGQMHGAVLLDAEGEVIRPAILWNDTRCAAECAELEEMAPELHQV AGNLAMPGFTAPKLLWVRRHEPQYFQRTATVLLPKDYLRYRMTGKKVSDMSDAAGTLWLD VAKRDWSDSLLDKCGLSRSQMPTLVEGCEVSATLDPQVAERWGLNASVAVAGGGGDNAVS AIGVGAVSPGDAFISLGTSGVLFVVTDAYRPAPQSAVHAFCHVLPNLWHQMSVMLSAASC LQWFCRLTGTTEVALLEEIAQLSEEEKAHAPFFLPYLSGERTPHNDPDARGMFWGMTHSS LRAQLGYAVLEGVSFGINDGLRVLKESGTRIEQCSLVGGGARSPFWAQLLADILDMPVVT HKGGETGGALGAARLACLAAGKPLAAVCEKPEVWQTWRADPVRHQTLMRRYAQFNALYLN DLNYRQH