Protein Info for BWI76_RS19325 in Klebsiella michiganensis M5al

Annotation: mandelate racemase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 384 PF02746: MR_MLE_N" amino acids 30 to 125 (96 residues), 36.2 bits, see alignment E=6.3e-13 PF13378: MR_MLE_C" amino acids 152 to 372 (221 residues), 183.3 bits, see alignment E=5.2e-58

Best Hits

KEGG orthology group: None (inferred from 98% identity to kpe:KPK_1626)

Predicted SEED Role

"mandelate racemase/muconate lactonizing enzyme family protein" in subsystem Catechol branch of beta-ketoadipate pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B6P9 at UniProt or InterPro

Protein Sequence (384 amino acids)

>BWI76_RS19325 mandelate racemase (Klebsiella michiganensis M5al)
MKIESVNVTVFQYPTRRVSDSAGHSHPGAESMAKMAMLTITADDGTRGFSFAPPEVVRPF
VVNTFFRKVMVGQDPFNRERIWQDLNHWQRGSAHQLTERALSFVEQALWDLIGRKLNMPV
YKLLGGYRDTVPAYGSTMCGDDLPGGLSTPEEYAAFAEKLVARGYKAIKLHTWMPPIAFA
PNPKMDIKACAAVREAVGPDIDLMIDGYHWYSRAEALWIGKELEKLNFAWFEEPMEEDSM
SSYAWLAENLSIPIVGPESFGGKHHMRAEWVKAGACDILRAGANGVGGITPTMKVAALAE
SFGMDCEVHGNGAASLAVVGAIRNCRWYERGLLHPFLDYDEPAAYLNSIVDPMDDQGFVH
LSQRPGLGEDINFAWIEANTVSHD