Protein Info for BWI76_RS18690 in Klebsiella michiganensis M5al

Annotation: PTS glucose transporter subunit IIBC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 transmembrane" amino acids 13 to 34 (22 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details amino acids 84 to 105 (22 residues), see Phobius details amino acids 125 to 149 (25 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 197 to 218 (22 residues), see Phobius details amino acids 230 to 246 (17 residues), see Phobius details amino acids 276 to 294 (19 residues), see Phobius details amino acids 306 to 322 (17 residues), see Phobius details amino acids 328 to 346 (19 residues), see Phobius details amino acids 353 to 373 (21 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details PF02378: PTS_EIIC" amino acids 11 to 346 (336 residues), 168.5 bits, see alignment E=2e-53 PF00367: PTS_EIIB" amino acids 437 to 468 (32 residues), 45.3 bits, see alignment (E = 4.5e-16)

Best Hits

KEGG orthology group: None (inferred from 81% identity to kpn:KPN_01683)

Predicted SEED Role

"PTS system, maltose and glucose-specific IIC component (EC 2.7.1.69) / PTS system, maltose and glucose-specific IIB component (EC 2.7.1.69)" in subsystem Maltose and Maltodextrin Utilization (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B6B9 at UniProt or InterPro

Protein Sequence (511 amino acids)

>BWI76_RS18690 PTS glucose transporter subunit IIBC (Klebsiella michiganensis M5al)
MIGVKKLQDFSKAMIGPVLYLPVIGLLIALLSMTTNKIWLAEDSSLYLLGKYVSSMLWAV
MNNLGFFFCLGLAGGLAKTRKAEAAFVAAMTWFMYLAANNSWLTLTQRLAAGASNAQLYG
SGQTYIFGFQVIDMGVFLGIILGCAVAFIHNRFVEIEFRGAFSIYGNSKLVLIIMIPLVG
VFAIATVYVWPIVEHGISALTGVMKTFGAAGVFLYGFLNRFLIPTGLHHLIWSPFVFTSI
GGQLLIDGQTVVGAKPIFLAEIANNTGAALSDSARFLTYGMVKIFGTAGMALAFYKTARP
ENKQKLKITLIPLIVTSFLVGITEPFEFLFIFTAPLLWLVYSLLDGFFQMLAWLLDVRVC
ATNGIIDFIVYNIPAGAHLTRWPVFVALGLMETAAMYYVGKFMIIHFKMPTPGQEQEVAV
VNQPPSAGSPDAASGEQVILGLGGKENVCSVDNCFTRLRVDVRDPALIQEHILKTSGGTS
VIIKGHHVQVIYGLGVNKIRNAVNRYLDVHE