Protein Info for BWI76_RS18675 in Klebsiella michiganensis M5al

Annotation: fimbrial protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 129 to 153 (25 residues), see Phobius details PF09160: FimH_man-bind" amino acids 25 to 169 (145 residues), 214.6 bits, see alignment E=5.1e-68 PF00419: Fimbrial" amino acids 180 to 297 (118 residues), 28.7 bits, see alignment E=1.6e-10

Best Hits

Swiss-Prot: 82% identical to FIMH_ECOLI: Type 1 fimbrin D-mannose specific adhesin (fimH) from Escherichia coli (strain K12)

KEGG orthology group: K07350, minor fimbrial subunit (inferred from 81% identity to kva:Kvar_0772)

Predicted SEED Role

"mannose-specific adhesin FimH"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B698 at UniProt or InterPro

Protein Sequence (301 amino acids)

>BWI76_RS18675 fimbrial protein (Klebsiella michiganensis M5al)
MKKIVTLLLTLLMAGWSLNAWSFACKTAAGVTIPIGGGSANVYVNLAPAVSVGQNLVVDL
STQIFCHNDFPETMIDYVTLQRGSAYGGLLSSFSGTVRYNGVSYPFPTTSETARMTYNSI
VDSPWPTVLYLTPISSAGGVAISAGSLIAVLILRQTNNKDNDDFQFVWNIYANNSVVVPT
GGCDVSARDVTVTLPEYPASAAIPLTVYCAQNQNLGYYLSGTTENAANSIFTNTASASPA
RGVGVQLTRNGSVVPANTTVSLGNVGTSAVSLGLTANYARTSGQVTAGNVQSIIGVTFVY
E