Protein Info for BWI76_RS18445 in Klebsiella michiganensis M5al

Annotation: glycosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 transmembrane" amino acids 246 to 267 (22 residues), see Phobius details amino acids 279 to 303 (25 residues), see Phobius details PF00535: Glycos_transf_2" amino acids 18 to 179 (162 residues), 92.3 bits, see alignment E=1.7e-30

Best Hits

Swiss-Prot: 52% identical to YKOT_BACSU: Uncharacterized glycosyltransferase YkoT (ykoT) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 85% identity to eta:ETA_19470)

MetaCyc: 39% identical to CPS-53 (KpLE1) prophage; bactoprenol glucosyl transferase (Escherichia coli K-12 substr. MG1655)
Phosphopolyprenol glucosyltransferase. [EC: 2.4.1.78]

Predicted SEED Role

"Glycosyltransferase"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.78

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B631 at UniProt or InterPro

Protein Sequence (330 amino acids)

>BWI76_RS18445 glycosyltransferase (Klebsiella michiganensis M5al)
MKEININNARSQIPSLAIVVPCYNEKDAFPYCLEGLTTILKNLLAKEKIARNSYILFVDD
GSKDNTWEQIKSTSQEKSFIRGLKLSRNRGHQIALLAGLANADTDVTVSIDADLQDDIGC
IEKMIDKYNEGFEIVYGVRDNRSSDSVFKRATANKFYSLMSGLGVNQVPNHADFRLLSRT
ALTALKDFKEQNLYLRGLIPLLGYKSSSVYYSRDERVAGESKYPLKKMVALALEGITSLT
ITPLRMIAAAGVITCLLSSLAAIYAFIEKILGNTVAGWTSVMIAIFFLGGVQMLSLGIIG
EYVGKIYMESKNRPKYFIEEVAKHEMRGEQ