Protein Info for BWI76_RS18380 in Klebsiella michiganensis M5al

Annotation: helix-turn-helix transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 transmembrane" amino acids 75 to 97 (23 residues), see Phobius details PF00196: GerE" amino acids 137 to 191 (55 residues), 59.9 bits, see alignment E=7.5e-21

Best Hits

Swiss-Prot: 75% identical to RCSA_KLEAE: Transcriptional regulatory protein RcsA (rcsA) from Klebsiella aerogenes

KEGG orthology group: None (inferred from 79% identity to eae:EAE_23070)

Predicted SEED Role

"Colanic acid capsular biosynthesis activation accesory protein RcsA, co-regulator with RcsB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5Q8 at UniProt or InterPro

Protein Sequence (207 amino acids)

>BWI76_RS18380 helix-turn-helix transcriptional regulator (Klebsiella michiganensis M5al)
MSTIIMDLCSFTRLGLTGYLTGRGVRKRDITEVHSAPSLKALCETSRPSVVFINEDCFIH
HEDSNQLIRQIISQYPATLFVIFMSLANIHFNHYLLVRKNLLICSKSLTEKDLDDILAIR
LKYENYRAARLNIPTLSLSQTESNMLQMWMAGHGTSHISAQMNIKAKTVSSHKGNIKKKI
HTHNKQVIYHIVRLTENITSGIHVNLR