Protein Info for BWI76_RS18240 in Klebsiella michiganensis M5al

Annotation: L-arabinose ABC transporter permease AraH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 22 to 44 (23 residues), see Phobius details amino acids 52 to 70 (19 residues), see Phobius details amino acids 77 to 94 (18 residues), see Phobius details amino acids 100 to 122 (23 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 168 to 189 (22 residues), see Phobius details amino acids 220 to 238 (19 residues), see Phobius details amino acids 250 to 267 (18 residues), see Phobius details amino acids 274 to 293 (20 residues), see Phobius details amino acids 299 to 318 (20 residues), see Phobius details PF02653: BPD_transp_2" amino acids 56 to 313 (258 residues), 136.3 bits, see alignment E=5.8e-44

Best Hits

Swiss-Prot: 92% identical to ARAH_ECOLI: L-arabinose transport system permease protein AraH (araH) from Escherichia coli (strain K12)

KEGG orthology group: K10538, L-arabinose transport system permease protein (inferred from 97% identity to kpu:KP1_3525)

MetaCyc: 92% identical to arabinose ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-2-RXN [EC: 7.5.2.12, 7.5.2.13]

Predicted SEED Role

"L-arabinose transport system permease protein (TC 3.A.1.2.2)" in subsystem L-Arabinose utilization (TC 3.A.1.2.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.12 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5P4 at UniProt or InterPro

Protein Sequence (326 amino acids)

>BWI76_RS18240 L-arabinose ABC transporter permease AraH (Klebsiella michiganensis M5al)
MSSVTTSGTTRSAFSFSRVWDQFGMLVVFAVLFIGCVIFVPNFASFINMKGLGLAISMSG
MVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESMWIGIGAGLLLGALSGLVNGF
VIARLKINALITTLATMQIVRGLAYIISDGKAVGIEDERFFTLGYANWFGLPAPIWLTVA
CLIVFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAAAGIILASR
MTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFS
QYVVRGVILLAAVIFDRYKQKAKRAV