Protein Info for BWI76_RS18220 in Klebsiella michiganensis M5al

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 527 transmembrane" amino acids 12 to 36 (25 residues), see Phobius details amino acids 48 to 66 (19 residues), see Phobius details amino acids 86 to 103 (18 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 151 to 173 (23 residues), see Phobius details amino acids 179 to 201 (23 residues), see Phobius details amino acids 251 to 273 (23 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 314 to 333 (20 residues), see Phobius details amino acids 339 to 358 (20 residues), see Phobius details amino acids 396 to 414 (19 residues), see Phobius details amino acids 426 to 446 (21 residues), see Phobius details PF13347: MFS_2" amino acids 13 to 451 (439 residues), 168 bits, see alignment E=2.7e-53 PF07690: MFS_1" amino acids 22 to 365 (344 residues), 62.5 bits, see alignment E=3.4e-21

Best Hits

KEGG orthology group: None (inferred from 93% identity to eae:EAE_22925)

Predicted SEED Role

"Rhamnogalacturonide transporter RhiT" in subsystem L-rhamnose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5X7 at UniProt or InterPro

Protein Sequence (527 amino acids)

>BWI76_RS18220 MFS transporter (Klebsiella michiganensis M5al)
MKTRKIGLVNYLAYGSGDFLGAGTTALTAAWLLYFYTTFCGLSPIEATLIFATARVLDAV
ISPLMGFLTDNFGSTWLGKRFGRRKFFILLGIPCVFSYSIMWVGDMGFWYYLLTYLLFDI
VYTMILVPYETLVPEMTDDFKQKTKFSGARISMAQMSAILASFLPGVLLTIFGKDNAVSF
FYASLVFSVLCAMMLTFVWFFTWERPREEWTEAALRAEEEKQNLTLSQSLNRLFIELSST
LRIKIFRQHLGMYLGGYIAQDVFNAVFTYYVVFVLMQEASMASNLLGTMAIFQFIAVIAM
IPLCIRFGPAPSYRMVVVLFGLSSLSYAVLYYAGLSDVYSLLLLISAVAGLGRGGINYVP
WNTYTYIADVDEVITGQRREGIFAGIMTLTRKASQAGAVMLVGIIMQMSGFVSGQKTQPY
EVSHTILLILSVGTLVVLACGFLVSLRFKLNLQTHSVLRAETLKMRESGRAQPELASAED
REVVEMLAGMPYDALWGNNNIGYLNRNKPAAPALKQRSAMNSTYNRG