Protein Info for BWI76_RS18075 in Klebsiella michiganensis M5al

Annotation: oligopeptidase B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 PF02897: Peptidase_S9_N" amino acids 3 to 404 (402 residues), 379 bits, see alignment E=2.6e-117 PF00326: Peptidase_S9" amino acids 463 to 674 (212 residues), 225.8 bits, see alignment E=4.4e-71

Best Hits

Swiss-Prot: 82% identical to PTRB_ECOLI: Protease 2 (ptrB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 89% identity to eae:EAE_22780)

MetaCyc: 82% identical to oligopeptidase B (Escherichia coli K-12 substr. MG1655)
Oligopeptidase B. [EC: 3.4.21.83]

Predicted SEED Role

"Protease II (EC 3.4.21.83)" (EC 3.4.21.83)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.21.83

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5W7 at UniProt or InterPro

Protein Sequence (686 amino acids)

>BWI76_RS18075 oligopeptidase B (Klebsiella michiganensis M5al)
MPPKAKRIPHAMTLHGDTRIDNYYWLRDDDRSQPEVLDYLRQENEYGKKVMSSQSSLQDR
VLKEIIDRIPQREVSAPYSKNGYRYRQVYEPGCEYAIYQRQPVVKEEWDEWDVLLDGNQR
AAGSEFYTLGGLGVSPDNSLMAVAEDYLSRRQYSLRFFPLNDDRQFAEVLENVSPDFAWS
NDSQTLWYVRKHPTTLLPYQVWRHRLGTPASADVLVYEEQDDTFYVSVHKTTSQQFVVIY
LASATTSEVLLLNAEMTDAEPVCFLPRRKDHEYSLDHYQHAFYLRSNREGKNFGLYRSTL
RDEQQWETLIAPRHEVMLEGFTLFTDWLVVEERQRGLTSLRQINRKTRESQGIAFDDPAY
VTWLAYNPEPETSRLRYGYSSMTTPDTLFELDMNTGERRVLKQQEVKGFDASHYRSEHLW
IIARDGVEVPVSLVYRDEHFRKGASPLLVYGYGSYGASMDADFSASRLSLLDRGFVFAIA
HIRGGGELGQQWYEDGKFLCKKNTFNDYLDVCDALLAQGYGDPRFCYGMGGSAGGMLMGV
AVNQRPELFHGVVAQVPFVDVLTTMLDESIPLTTGEFEEWGNPQDEDYYRYMKSYSPYDG
VQAQTYPHLLVTTGLHDSQVQYWEPAKWVAKLRALKTDDNLLLLCTDMDSGHGGKSGRFK
SYEGVALEFAFLIGLAQGTLPGQAEV