Protein Info for BWI76_RS17855 in Klebsiella michiganensis M5al

Annotation: alginate lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 676 PF05426: Alginate_lyase" amino acids 96 to 270 (175 residues), 24.3 bits, see alignment E=2.1e-09 PF07940: Hepar_II_III" amino acids 367 to 586 (220 residues), 58.7 bits, see alignment E=6.9e-20

Best Hits

KEGG orthology group: None (inferred from 84% identity to kva:Kvar_1856)

Predicted SEED Role

"FIG01220424: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5G5 at UniProt or InterPro

Protein Sequence (676 amino acids)

>BWI76_RS17855 alginate lyase (Klebsiella michiganensis M5al)
MKQFSGLWPDIVGRAAANSGLLERLVKDAQPVLQAAVRIPQSGIASWNLYYFCPRHGVRL
TWRADTPYQHACPVDGEIFSGEPWDGAWWREMNGRNASACQQLGLLWRLTGETAYRDKVR
TLLMGYADVYPGYAIHGDIPNNGPGKMNAQTLCEANCILEMALGYDFIRDSLPPGEQRHI
SENLLRCAATFLRDHRSPQIHNHEVKISAALGVLGFVLEDEALLEFAVNQPYGLRWQLEN
GLLAEGLWFEGSIHYHYYALQGFFAFEKLARGTRWSLLDGPWYQAMLKFPLALLLPDGTF
PRLNDCLAGQEKLHHRDLYEFAWFIWRDPQYAAVLQFTETAPDERETLLWRERSLPESPL
ALIPQQSLFAPGAGLTLWRRPQQALLIKHSPWGGEHDHYDRLGLMLWHRDGWLLTDMGTT
GYGAKMHYDYYKNSATHNTLCVNQSNQPPANPQVLGRHMDDDFLWLDSEVDWGKPPPELN
SHSRVEWDATAWRDVRFRRRLLWLEDVLIDLSSVENPHRQQLDWTLHLAAQALDQSGTAR
PFSLSGPLRRMTEATVTPLNGCQPRHFARGGDTVALWLSGDGELWQGLAPDNPAIRNLSY
LVIRNHLPQARFVCLWDLANSAPLTEVNVHHTPVGTQITFWRGDRVTHVTLYDEPGKRPD
AILPLAESGVSPQYAE