Protein Info for BWI76_RS17845 in Klebsiella michiganensis M5al

Annotation: extracellular solute-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF13531: SBP_bac_11" amino acids 34 to 333 (300 residues), 28.1 bits, see alignment E=3.3e-10 PF01547: SBP_bac_1" amino acids 40 to 332 (293 residues), 143.6 bits, see alignment E=2.9e-45 PF13416: SBP_bac_8" amino acids 46 to 343 (298 residues), 119 bits, see alignment E=7.1e-38

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 93% identity to kva:Kvar_1858)

Predicted SEED Role

"Putative sugar binding protein, ABC transport system precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5P3 at UniProt or InterPro

Protein Sequence (429 amino acids)

>BWI76_RS17845 extracellular solute-binding protein (Klebsiella michiganensis M5al)
MSANKLRSLLLLTALGLGVSQSYAATTLNVWIRASNDSKNIYKQEAEKFEEKTGIKIEYF
NATTDFEQRLARATAGNALPDLIFNDAASLGQFIQLGIAEEIDPQAIAGGDQLFQTAWKS
TRYIDGKYYGVPTSAQTFALFVRKDWREKLGLPQPKSWDDIQALAKAFTTQDPDGNGKND
TYGFIVPASTTRGYASWFMSSFIWQAGGDFVKEESGKFSASLNTPEVAQAMTFMRAMMCD
KVTQPGAINATTADVIPSFRSGQSGMFFSGPYHIALFDKDPGKDNFEVIPVVGPKGEATL
AEGTTVFMMKSSVQKEAARQFIEFMISPEGQEIGMGKGSQHIPVVRLPVNKNVDVKAVYQ
DARWETFARLYNEQGRYVPQIPNWTPVRQVAAEGFNRIFADCSSDIPGELKTLDGKVNAE
LKKQNVLAN