Protein Info for BWI76_RS17805 in Klebsiella michiganensis M5al

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 194 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR00752: outer membrane lipoprotein, Slp family" amino acids 11 to 188 (178 residues), 233.9 bits, see alignment E=4.4e-74 PF03843: Slp" amino acids 20 to 173 (154 residues), 147.5 bits, see alignment E=1e-47

Best Hits

Swiss-Prot: 77% identical to YEAY_ECOLI: Uncharacterized lipoprotein YeaY (yeaY) from Escherichia coli (strain K12)

KEGG orthology group: K07285, outer membrane lipoprotein (inferred from 90% identity to kpn:KPN_02323)

Predicted SEED Role

"Starvation lipoprotein Slp paralog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5F5 at UniProt or InterPro

Protein Sequence (194 amino acids)

>BWI76_RS17805 membrane protein (Klebsiella michiganensis M5al)
MAGQKRVVRWLVAAAVVAALSGCASVPDAIKGTTPTPQQDLVRVMNAPQLYVGQEARFGG
KVVSVQNQQGKTRLEIATVPLDGAARPALGEPSRGRIFADVNGFIDPVDFRGQLVTVVGP
IVGVVDGKVGNTPYKFMLMNAIGYKRWNVVQQVVMPPQPMMDPWMFGPRPWGYGYGGWGW
YNPGPAEVRNVVTE