Protein Info for BWI76_RS17525 in Klebsiella michiganensis M5al

Annotation: XshC-Cox1-family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 277 PF02625: XdhC_CoxI" amino acids 12 to 74 (63 residues), 76.8 bits, see alignment E=9.8e-26 PF13478: XdhC_C" amino acids 106 to 247 (142 residues), 111.5 bits, see alignment E=4.1e-36

Best Hits

KEGG orthology group: K07402, xanthine dehydrogenase accessory factor (inferred from 79% identity to cro:ROD_33981)

Predicted SEED Role

"Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B599 at UniProt or InterPro

Protein Sequence (277 amino acids)

>BWI76_RS17525 XshC-Cox1-family protein (Klebsiella michiganensis M5al)
MNIFEEAARLEEQNRPFALAQIVESRGSTPRHAAQMLIREDGSIVGTIGGGMVERKVIDA
AQAALRERESRMFHGRMARTGSDAVGSDCGGAMSVYISVHGLRPRLLLVGAGHVNRAVAH
AAALLDFDICVGDTYAASLCPDAFPASARLAHAASFTDVVEAMAVRPQDFVLIATNNQDW
EALDRLITQPVAWLGLLASRRKVQAFVRQLRENGVPEADISRLRAPIGYDIGAETPNEIA
ISVLAEILQVKNGAPGGLMNQVKQAGQQEYAVETVEI