Protein Info for BWI76_RS17445 in Klebsiella michiganensis M5al

Annotation: outer membrane lipoprotein LolB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 203 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details TIGR00548: outer membrane lipoprotein LolB" amino acids 3 to 202 (200 residues), 288.4 bits, see alignment E=1.3e-90 PF03550: LolB" amino acids 46 to 200 (155 residues), 152.7 bits, see alignment E=4e-49

Best Hits

Swiss-Prot: 93% identical to LOLB_KLEP3: Outer-membrane lipoprotein LolB (lolB) from Klebsiella pneumoniae (strain 342)

KEGG orthology group: K02494, outer membrane lipoprotein LolB (inferred from 92% identity to kpn:KPN_02236)

MetaCyc: 84% identical to outer membrane lipoprotein LolB (Escherichia coli K-12 substr. MG1655)
RXN-22553

Predicted SEED Role

"Outer membrane lipoprotein LolB precursor"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B5D9 at UniProt or InterPro

Protein Sequence (203 amino acids)

>BWI76_RS17445 outer membrane lipoprotein LolB (Klebsiella michiganensis M5al)
MNRLFRLLPLASLVLTACAINAPKGPGKSPDSPQWRQHQQDVRNLNQFQTRGAFAYLSDE
QKVYARFFWQQTGQDRYRLLLTNPLGSTELSLTAQPGNVQLIDNKGQTYTATDAEEMIGR
LTGMPIPLNSLRQWIIGLPGDATDYSLDDQYRLRELNYTQNGKTWHVTWGGYTSDTKPSL
PANMELNDGSQRIKLKMDNWIVK