Protein Info for BWI76_RS17355 in Klebsiella michiganensis M5al

Annotation: YchO family inverse autotransporter domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 459 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF11924: IAT_beta" amino acids 58 to 334 (277 residues), 342 bits, see alignment E=1.6e-106

Best Hits

Swiss-Prot: 66% identical to YCHO_ECOLI: Uncharacterized protein YchO (ychO) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 83% identity to eae:EAE_16810)

Predicted SEED Role

"Invasin"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B555 at UniProt or InterPro

Protein Sequence (459 amino acids)

>BWI76_RS17355 YchO family inverse autotransporter domain-containing protein (Klebsiella michiganensis M5al)
MSSLPFRVTPLLPLLLLLTGMPARALQDNQAFSKGPETLPDLGLAPQVDDDAKHFAEMAK
KFGEASMSDNGLTTSEQARVFAIGKLGNEVSHQLENWLSPWGNANVDLLVDKEGNFTGSK
GSWFVPLQDNGDYLTWNQYSVTQRDTGLVGNIGLGQRWRMGSWLLGYNSFYDKALDDRMA
RGSVGAEAWGESLRLSANYYQPLGSWQQGSSLTQQQRMASGYDVTAQARLPFYQHINTSV
SVEQYFGDSVDLFHSGTGYHNPVAVSVGLNYTPVPLVTVTAKHKQGESGVSQNDVGLKLN
YRFGVPLKQQLAADEVAVSRSLRGSRYDSPERDNLPVVEYRQRKTLSVYLATPPWDLQPG
ETVQLKLQIRSLHGIKSLSWQGDTQALSLTSPIEANSTDGWTVIMPRWSSEAGASNRWHL
SLVVEDKTGQRVSSNEIALALTEPLVHVPAEGVSWPQQP