Protein Info for BWI76_RS17145 in Klebsiella michiganensis M5al

Annotation: translation initiation factor IF-3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 180 TIGR00168: translation initiation factor IF-3" amino acids 15 to 179 (165 residues), 249 bits, see alignment E=8.7e-79 PF05198: IF3_N" amino acids 15 to 84 (70 residues), 109.8 bits, see alignment E=5.7e-36 PF00707: IF3_C" amino acids 91 to 177 (87 residues), 121 bits, see alignment E=1.7e-39

Best Hits

Swiss-Prot: 96% identical to IF3_ECO27: Translation initiation factor IF-3 (infC) from Escherichia coli O127:H6 (strain E2348/69 / EPEC)

KEGG orthology group: K02520, translation initiation factor IF-3 (inferred from 99% identity to kva:Kvar_2012)

Predicted SEED Role

"Translation initiation factor 3"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B575 at UniProt or InterPro

Protein Sequence (180 amino acids)

>BWI76_RS17145 translation initiation factor IF-3 (Klebsiella michiganensis M5al)
MKGGKRVQTARPNRINGEIRALEVRLTGLEGEALGIVSLREAIEKAEEAGVDLVEISPNA
EPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDDGDYQVKLRSLVRFLEE
GDKAKITLRFRGREMAHQQIGMEVLTRVRDDLSELAVVESFPTKIEGRQMIMVLAPKKKQ