Protein Info for BWI76_RS16995 in Klebsiella michiganensis M5al

Annotation: Fe-S cluster assembly protein SufB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 TIGR01980: FeS assembly protein SufB" amino acids 21 to 486 (466 residues), 640.2 bits, see alignment E=7.7e-197 PF19295: SufBD_N" amino acids 156 to 217 (62 residues), 48.4 bits, see alignment E=8.9e-17 PF01458: SUFBD_core" amino acids 225 to 466 (242 residues), 259.2 bits, see alignment E=3.5e-81

Best Hits

Swiss-Prot: 94% identical to SUFB_ECOLI: FeS cluster assembly protein SufB (sufB) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to eae:EAE_17130)

Predicted SEED Role

"Iron-sulfur cluster assembly protein SufB" in subsystem Staphylococcal phi-Mu50B-like prophages

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B4Y3 at UniProt or InterPro

Protein Sequence (495 amino acids)

>BWI76_RS16995 Fe-S cluster assembly protein SufB (Klebsiella michiganensis M5al)
MSRNTEATDDVKTWSGGPLNYKEGFFTQLQTDELAKGINEEVVRAISARRNEPEWMLEFR
LNAFKAWQAMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDACASEPGALQQTGSSAFLT
NEVEEAFNLLGVPVREGREVAVDAIFDSVSVATTYREKLAEQGIIFCSFGEAIHEHPELV
QKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEGSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKDAEVKYSTVQNWFPGDNNTGGILNF
VTKRALCEGENSKMSWTQSETGSAITWKYPSCILRGDNSIGEFFSVALTSGHQQADTGTK
MIHIGKNTRSTIISKGISAGHSQNSYRGLVKIMPTATNARNFTQCDSMLIGPDSGAHTFP
YVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEDDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG