Protein Info for BWI76_RS16835 in Klebsiella michiganensis M5al

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 717 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details PF07715: Plug" amino acids 76 to 172 (97 residues), 66.2 bits, see alignment E=3.6e-22 TIGR01783: TonB-dependent siderophore receptor" amino acids 77 to 717 (641 residues), 371.3 bits, see alignment E=5.5e-115 PF00593: TonB_dep_Rec" amino acids 244 to 684 (441 residues), 234.7 bits, see alignment E=4e-73

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 87% identity to kpe:KPK_2218)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B4Y6 at UniProt or InterPro

Protein Sequence (717 amino acids)

>BWI76_RS16835 TonB-dependent siderophore receptor (Klebsiella michiganensis M5al)
MIPLNVPFSALKGRALFSLIFFTSPGLVAAENSTTQTKKTTDETMTVVADGSRQSATNGY
QPVNTSTATLTTMPMLDIPQVVNTVSEQVLEDQHATNLDEALYNVANVVQTNTLGGTQDA
FSRRGFGANRDGSIMTNGLRTVLPRSFTAATERVEVLKGPASTLYGILDPGGLINVVTKR
PERSFGGSVSATSTSFGGGSGQFDVTGPIDGTPLAYRVIGEYQHEDYWRNFGKQKTSFIN
PSLTWFGERATVNVSYSHRNYSTPFDRGTIFDLNTGHAVNVDRKTRFDEPFNITDGYSDL
AQLNAEYRLSDAWTARFDYSYSQDHYNDDQARVMAYDSATGNLTRRVDATHGSTQKMHAT
RADLQGNVVIGGFYNEILTGLAYENYDLLRTDMIRCKNVKGFNIYNPVYGTLDKCSSVSA
SDSDQRTQQESYAGYVQDALYLSDKWIAIAGVRYQYYTQYAGKGRPFNVNTDSSDQKWTP
KAGLVYKLTPSVSLFGNVAQSFMPQSSIASYIGNLPPEESTSYELGAKFELFNGVTANIA
LFDIDKRNVLYTESVGDETVAKTAGKVRSRGVEVDVAGSLTDNLSVIASYGYTDAKVTDD
PDYKGKPLPNVPKHTGSVFLSYDIHNVYDSNTLTVGGGGRAVSKRSGTNGADYYLQGYAV
ADVFAAYKMKLQYPVTLQVNVKNLFDKTYYTSSIGTNNLGNQIGDPREVQFTLKMDF