Protein Info for BWI76_RS16680 in Klebsiella michiganensis M5al

Annotation: ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 567 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF00496: SBP_bac_5" amino acids 104 to 485 (382 residues), 276.6 bits, see alignment E=1.7e-86

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 92% identity to pao:Pat9b_4560)

Predicted SEED Role

"Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)" in subsystem ABC transporter oligopeptide (TC 3.A.1.5.1) or Sex pheromones in Enterococcus faecalis and other Firmicutes (TC 3.A.1.5.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B589 at UniProt or InterPro

Protein Sequence (567 amino acids)

>BWI76_RS16680 ABC transporter substrate-binding protein (Klebsiella michiganensis M5al)
MSRLLHGLKTKQTRFALALKIALLGGAVAFSSVAIADDILKEGITPASDASQIPAAAKLR
KDTVVAGISEPQGIFNPYFFVNGWDENVTNVIFSRLIDWDSHGKLVPGLAESWTVSPDNK
VYTIKLRPNLTFSDGSPLTAEDVAFTLTVLLDPKYDGDTDITLANIAGGADYKAGKADSV
SGLKVVDPLTLQVTTTQPGATTLAKIGGPVLSKAYYGKGYQRGNLDYLRTLHGKPLGNGP
YVYDKYIPGQEIRFHANSHFYRRTPPTPRFIYRVTNPSTNFQLFQTGETDYDAFTSRPDD
IEQLKMLGFANINLYGSSDYSQVEFNVRRPALQDVKVRQALIYGLDRQKLIDVVYQGYGK
VAIEPIAPISWAYNADGVNPYHYDPAQAKKLLDEAGWKPGADGIRVKEGKRLELTLLVSK
KVLNDALIPIAKENWQQIGVLLKPQVVDFNALMAQRKSGNYDLASFSTSTLNDPHDGVWD
FYSAEAKESGYNNPQVDKLITEGNSVLDVEKRKPIYHQLYQVLAQDPPVILLGYREILSA
SSARVSGFKPDIYNGLTGSLPDVKIVK