Protein Info for BWI76_RS16675 in Klebsiella michiganensis M5al

Annotation: ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 PF00005: ABC_tran" amino acids 27 to 175 (149 residues), 130.7 bits, see alignment E=1.2e-41 PF09383: NIL" amino acids 266 to 316 (51 residues), 35 bits, see alignment 2.1e-12

Best Hits

Swiss-Prot: 49% identical to METN2_SALTY: Methionine import ATP-binding protein MetN 2 (metN2) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K02071, D-methionine transport system ATP-binding protein (inferred from 75% identity to kva:Kvar_2277)

Predicted SEED Role

"Methionine ABC transporter ATP-binding protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B515 at UniProt or InterPro

Protein Sequence (348 amino acids)

>BWI76_RS16675 ABC transporter (Klebsiella michiganensis M5al)
MTQKPNPTTHIQLSQISKAYPNGVQALRDINLQIAQGEIFGIIGRSGAGKSTLLRLFNRL
ENADSGEITIHGEHTRHYSRSQLRDLRRRVAMIFQHFNLMATKTVAQNVELPLKMAGVPR
AERQKRVDEILALVGLSALRDSWPAKLSGGQKQRTGIARALVTQPEILLCDEATSALDPE
NTHAVLKLLKEINQRLGLTIVLITHEMDVIRTLCDRVAVLEHGEIIEQGEVWRVFGHPGH
AVTRSLLGTLHHDRAEERLSLSENQQLVTLHFDGSSGQEPDLQRIAALLGADARLLYGSC
EQIQGRVIGQLRIRLAKPLANPHLQQHAGWVADRLTLSGDTAAENAGA