Protein Info for BWI76_RS16585 in Klebsiella michiganensis M5al

Annotation: trehalose synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 541 PF00128: Alpha-amylase" amino acids 27 to 376 (350 residues), 211.1 bits, see alignment E=1.6e-66

Best Hits

KEGG orthology group: K05343, maltose alpha-D-glucosyltransferase [EC: 5.4.99.16] (inferred from 82% identity to enc:ECL_02049)

Predicted SEED Role

"Trehalose synthase (EC 5.4.99.16)" in subsystem Trehalose Biosynthesis (EC 5.4.99.16)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.99.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B4Y9 at UniProt or InterPro

Protein Sequence (541 amino acids)

>BWI76_RS16585 trehalose synthase (Klebsiella michiganensis M5al)
MADWHTRAIIYQIDSALFYDFNSDGCGDIAGITAKLRYIRRMGATVIWITPFYLTPFLDE
GYDVSDHLQVDPRFGQLADIIAFIEQARELGMQVIIELLIQHTSDAHPWFQRARRSRSSP
FRDYYLWADSDDDDTPPMFPGVEESIWTWDEEAGQYFRHMFYRHEPDLNLASPAVIKEVE
NIIIFWLKLGVSGFRLDAAAHLTKQAGRGEEKRGLWILEHLRRLVERHNPQAILLGEVDV
DVEQYRDYFGDNNRLNMVLNFWLNKYFYVSLASQNARPLINAIKKTIVPPDACCFANWLR
NHDELDLEGIGNKNKQTVLEAFAPDEKMNVYQRGIRRRLAPMLNGNRQRLAFCHAVLFSL
PGVPIMRYGDEIGMGDDLALEERYAVRTPMQWAGSAGGGFSAADPDTFVAPMIDRGPFRY
QKVNVADSLLHRHSLLHRIMDIANTRSEFPEIAVAPFRIISTDRQAILAICYDNHERSVI
TFLNFSEKALRFTAKGIDEAVWTPCLADKTYADALIPGKRVELEISAYGYRWFWTNSSAL
R