Protein Info for BWI76_RS16580 in Klebsiella michiganensis M5al

Annotation: ubiquinol oxidase subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 336 transmembrane" amino acids 7 to 37 (31 residues), see Phobius details amino acids 61 to 100 (40 residues), see Phobius details amino acids 117 to 139 (23 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 199 to 218 (20 residues), see Phobius details amino acids 230 to 248 (19 residues), see Phobius details amino acids 260 to 281 (22 residues), see Phobius details amino acids 301 to 323 (23 residues), see Phobius details PF02322: Cyt_bd_oxida_II" amino acids 6 to 325 (320 residues), 337.9 bits, see alignment E=3.1e-105 TIGR00203: cytochrome d ubiquinol oxidase, subunit II" amino acids 7 to 213 (207 residues), 145.7 bits, see alignment E=1.1e-46

Best Hits

KEGG orthology group: K00426, cytochrome bd-I oxidase subunit II [EC: 1.10.3.-] (inferred from 86% identity to enc:ECL_02048)

Predicted SEED Role

"putative Cytochrome bd2, subunit II" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B4R1 at UniProt or InterPro

Protein Sequence (336 amino acids)

>BWI76_RS16580 ubiquinol oxidase subunit II (Klebsiella michiganensis M5al)
MGIDIPVIWFVIIVFATLMYIVMDGFDLGIGMVFSFVPNANERDVMMNSVAPVWDGNETW
LVLGGAGLFGAFPLAYAVIADALTIPLTAMLIGLIFRGVAFEFRFKATPSHQKFWDYSFV
GGSLLATFSQGIVVGAVISGFDVADRRFIGSALDWLTPFSLFCGLGLVVAYTLLGTTWLI
MKSEGALQQRMRELTRRTLLALLAVIAVVSVWTPLGWHSVAERWFTLPNFYWFVPVPILV
LVFSLWIWRLSANPNSHARPFLLTLGLIFLGFSGLGISLWPNIIPPHITLWEASAPPASQ
LFMLVGTLLIIPVILVYTAWSYYVFRGKVSGNEGYH