Protein Info for BWI76_RS16390 in Klebsiella michiganensis M5al

Annotation: dipeptide/tripeptide permease A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 transmembrane" amino acids 23 to 48 (26 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 90 to 107 (18 residues), see Phobius details amino acids 113 to 131 (19 residues), see Phobius details amino acids 152 to 173 (22 residues), see Phobius details amino acids 179 to 200 (22 residues), see Phobius details amino acids 221 to 239 (19 residues), see Phobius details amino acids 245 to 264 (20 residues), see Phobius details amino acids 275 to 294 (20 residues), see Phobius details amino acids 323 to 341 (19 residues), see Phobius details amino acids 353 to 371 (19 residues), see Phobius details amino acids 385 to 408 (24 residues), see Phobius details amino acids 417 to 438 (22 residues), see Phobius details amino acids 457 to 478 (22 residues), see Phobius details TIGR00924: amino acid/peptide transporter (Peptide:H+ symporter)" amino acids 17 to 485 (469 residues), 463.7 bits, see alignment E=4.2e-143 PF07690: MFS_1" amino acids 35 to 434 (400 residues), 63.9 bits, see alignment E=1.3e-21 PF00854: PTR2" amino acids 89 to 447 (359 residues), 318.4 bits, see alignment E=6.7e-99

Best Hits

Swiss-Prot: 90% identical to DTPA_CITK8: Dipeptide and tripeptide permease A (dtpA) from Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)

KEGG orthology group: K03305, proton-dependent oligopeptide transporter, POT family (inferred from 90% identity to cko:CKO_01646)

MetaCyc: 91% identical to dipeptide/tripeptide:H+ symporter DtpA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-267; TRANS-RXN0-288

Predicted SEED Role

"Di/tripeptide permease DtpA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B4Z0 at UniProt or InterPro

Protein Sequence (501 amino acids)

>BWI76_RS16390 dipeptide/tripeptide permease A (Klebsiella michiganensis M5al)
MSTANNKPTESVSLNAFKQPRSFYLIFSIELWERFGFYGLQGIMAVYLVKQLGMSEADSI
TLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGYGLVAWSGHDAGIVYIGMA
TIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSINIGSFFSMLATPWLAAKFGWS
VAFALSFVGLVITIVNFTFCQRWVKQYGSKPDFAPLQVGKLLATIVGVVVLIAIATWLLH
NQGVARMALGVVALGIIVIFAKEAFAMQGAARRKMIVAFILMLQAIIFFVLYSQMPTSLN
FFAIRNVEHSLLGIAFEPEQYQALNPFWIIIGSPILAAIYNKMGDTLPMPMKFAIGMVLC
SGAFLVLPLGAKFASDAGIVNVSWLVISYGLQSIGELMISGLGLAMVAQLVPQRLMGFIM
GSWFLTTAGANLIGGYVANMMAVPDNVTDPLMSLEVYGRVFLHIGVATGIIAILMLLTAP
KLNRMTQDDDKTAKARDTATA