Protein Info for BWI76_RS15955 in Klebsiella michiganensis M5al
Annotation: transcriptional regulator
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 85% identical to MLC_ECOLI: Protein mlc (mlc) from Escherichia coli (strain K12)
KEGG orthology group: None (inferred from 93% identity to kva:Kvar_2783)Predicted SEED Role
"Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon" in subsystem Maltose and Maltodextrin Utilization
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B4N4 at UniProt or InterPro
Protein Sequence (406 amino acids)
>BWI76_RS15955 transcriptional regulator (Klebsiella michiganensis M5al) MVADSQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRFAQLAPASITKIVREMLEAHLV QETEIQEPGSRGRPAVGLMVETEAWHYLSIRISRGELHLALRDLSSALVVEEQLELALQH VQPFATRLLDHVDQFFIRHQKKLERLTAIAVTMPGIIDTEHGIIHRMPFYEDVKDMPLGE ILANHTGVSVYIQHDISAWTMAESLFGASRGARDVIQVVIDHNVGAGVITDGRLLHAGSS SLVEIGHTQVDPYGKRCYCGNHGCLETIASVESVLELAQIRMAKSMSSMLHQQPLSVEWL CQAALQGDLLARDIISGVGNHVGRILAIMVNLFNPQKILIGSPFNLAADILFPAISDCIR QQSLPAYSRHIAVESTQFSNRGTMAGAALVKDALYNGSLLIRLLQG