Protein Info for BWI76_RS15860 in Klebsiella michiganensis M5al

Annotation: adenine-specific DNA methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 PF05063: MT-A70" amino acids 5 to 92 (88 residues), 48.6 bits, see alignment E=4.7e-17 amino acids 122 to 197 (76 residues), 33 bits, see alignment E=2.9e-12

Best Hits

KEGG orthology group: None (inferred from 93% identity to kpe:KPK_4187)

Predicted SEED Role

"Adenine DNA methyltransferase, phage-associated"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (219 amino acids)

>BWI76_RS15860 adenine-specific DNA methyltransferase (Klebsiella michiganensis M5al)
MSRKYSLIYADPPWAYGNTISNGAAVDHYSTMRLIDLKRLPVWELAAENAVLAMWYTGTH
NQEAIELAEAWGFTVRTMKGFTWVKLNQLAELRITKALAEGEVADFYDFLDLLNAETRMN
GGNHTRANTEDVLIATRGAGLERKHAGIKQVVYSPLGAHSEKPWEVRHRLELLYGDVPRI
ELFSRSAAPGWSHWGNQCATASVELIPGCAIDVVKTEAA