Protein Info for BWI76_RS15275 in Klebsiella michiganensis M5al

Annotation: isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 263 TIGR00654: phenazine biosynthesis protein, PhzF family" amino acids 4 to 234 (231 residues), 102.5 bits, see alignment E=1.4e-33 PF02567: PhzC-PhzF" amino acids 9 to 255 (247 residues), 160.7 bits, see alignment E=2.8e-51

Best Hits

Swiss-Prot: 48% identical to Y2770_PSEAE: Uncharacterized isomerase PA2770 (PA2770) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K06998, (no description) (inferred from 83% identity to kpn:KPN_01629)

Predicted SEED Role

"Phenazine biosynthesis protein PhzF" in subsystem Phenazine biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B4H2 at UniProt or InterPro

Protein Sequence (263 amino acids)

>BWI76_RS15275 isomerase (Klebsiella michiganensis M5al)
MQEISFYLVDAFSDRNFGGNAAAVCPLTEWLPDETLLKMAQQHNQSETAFFVRTDEGYEL
RWFTTLDEINLCGHATLAASHVIFEYFDHPSSTIVFSTRFVGELRVTRSGDWLTLDFPAW
ATTVVEQPPTELLAGLGLSDAVDVRVARDYLVILADRQQVEAVRPDMPMLQRLGKMICVS
AADEEYDFVSRFFCPGESVAEDPVTGSAHSMLIPYWGEKLGKTEMQARQGAARGGDLRCQ
WRGDRVLIGGQATTYLIGTITLR