Protein Info for BWI76_RS14850 in Klebsiella michiganensis M5al

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF00356: LacI" amino acids 5 to 50 (46 residues), 44.6 bits, see alignment 2e-15 PF00532: Peripla_BP_1" amino acids 62 to 319 (258 residues), 92.3 bits, see alignment E=7.8e-30 PF13407: Peripla_BP_4" amino acids 64 to 277 (214 residues), 46.9 bits, see alignment E=5.7e-16 PF13377: Peripla_BP_3" amino acids 176 to 335 (160 residues), 92.2 bits, see alignment E=8.2e-30

Best Hits

KEGG orthology group: None (inferred from 57% identity to ach:Achl_4610)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B443 at UniProt or InterPro

Protein Sequence (343 amino acids)

>BWI76_RS14850 LacI family transcriptional regulator (Klebsiella michiganensis M5al)
MRKATMRDVSEATGFSMFTVSRALNGGDGVADDSRELILKVARELGYVPNRAAQALRRSS
RDSVAVITAHASNSYYLNLMSGIQQMLQPSQWTVVLGDIAVNGIYDRAQEDRMINRLIES
RMAGIISTVTLQPESLSLLAKWDIPVVFVDSPPRGEHNFPSVTTDNYHASLLVGNHLAQH
GYKNWLLLIYPDRWTTRFERERGIREAAEQCGATLEVLETENDAQSASEKLSQYLARGEA
LPDVLIAGNNPILLGSLNQLQQRQIAIPGDMALIAYDEFDWAPLLNPPLTVLNENSEEIG
RQAAEMLIRLINQEGKGEIETQLKVPAALVIRQSCGCRKAHNT