Protein Info for BWI76_RS14595 in Klebsiella michiganensis M5al

Annotation: cytochrome-c peroxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF00532: Peripla_BP_1" amino acids 68 to 333 (266 residues), 135 bits, see alignment E=7.3e-43 PF13407: Peripla_BP_4" amino acids 71 to 317 (247 residues), 50.1 bits, see alignment E=5.8e-17 PF13377: Peripla_BP_3" amino acids 177 to 336 (160 residues), 118.5 bits, see alignment E=6.5e-38

Best Hits

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 98% identity to kpu:KP1_2774)

Predicted SEED Role

"regulatory protein, LacI:Periplasmic binding protein/LacI transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B470 at UniProt or InterPro

Protein Sequence (340 amino acids)

>BWI76_RS14595 cytochrome-c peroxidase (Klebsiella michiganensis M5al)
MAQEMSIKRVLLSDVAKLAGLSKATLSRYMNNSIVLPQDTIDRIETAIRELDYRGNSLAR
RLSKGGSETLGLVLPDITNPFFAELADAAEEAASASGYSLVLCITRNNPEKECQFIRWLD
TCQVDGLLFTTNRPDNGLLRKEVQRHERIVLLDEDIPGSTVPKVFADNVQGGRIATEKLI
AAGHRHIAFVGGPDKLMSVRERYQGFCTAMEQAGLSWPPEWVMYGDYQREFGQQALRYLF
SQPLRPTAVFAASDYLVLGLLDGLRASGLQAPEALSLVGFDDANYADFTQPRISTIRQPA
RELGRTAVNIMMRLLNNDQDIPAETRLPVEWIGRDSIKIC