Protein Info for BWI76_RS14460 in Klebsiella michiganensis M5al

Annotation: MurR/RpiR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 285 transmembrane" amino acids 133 to 152 (20 residues), see Phobius details amino acids 236 to 256 (21 residues), see Phobius details PF01418: HTH_6" amino acids 1 to 74 (74 residues), 43.1 bits, see alignment E=3.5e-15 PF01380: SIS" amino acids 127 to 235 (109 residues), 49.2 bits, see alignment E=4.7e-17

Best Hits

KEGG orthology group: None (inferred from 88% identity to pao:Pat9b_1138)

Predicted SEED Role

"transcriptional regulator, RpiR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (285 amino acids)

>BWI76_RS14460 MurR/RpiR family transcriptional regulator (Klebsiella michiganensis M5al)
MNLRENIVSQFSLLSPELQRAAEFSLQNANQLVVQSMRAFAAEAGVKPATLLRLAQRLGY
NGWRELKSAFIDDLGLGNDTYVSKAEKLIAKGTQPALYEEVFLAHQANLAFTQAENQHAM
QQAVRLLDEAKQVYICGFRASFPIAWSLFYVYRLFNRQVSLIDGLASNIEVFTREINAED
CLLLTSFSPYSRESLDVLNAARQAGARIIAITDSPVSPLAQTADCTLLFSLSSPSFFPSI
VSGMGVAECLLAMLVARHGREAVNKIESAERYLQRSGAYVMPDKS