Protein Info for BWI76_RS14165 in Klebsiella michiganensis M5al

Annotation: trans-acting regulatory protein of aco operon

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 917 PF17874: TPR_MalT" amino acids 483 to 822 (340 residues), 77.9 bits, see alignment E=9e-26 PF00196: GerE" amino acids 856 to 908 (53 residues), 74.2 bits, see alignment 5.1e-25

Best Hits

KEGG orthology group: K03556, LuxR family transcriptional regulator, maltose regulon positive regulatory protein (inferred from 79% identity to kva:Kvar_4120)

Predicted SEED Role

"FIG00731676: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3Z4 at UniProt or InterPro

Protein Sequence (917 amino acids)

>BWI76_RS14165 trans-acting regulatory protein of aco operon (Klebsiella michiganensis M5al)
MKPSDVKSRQATSLVSGPLRLTRDLPLILTKFVPPRSSIRLLQRSRLLLLLDRMQQRRLG
VVCAGAGFGKTTLLAQWYQHMIAQGERVAWLSLDEDDDGVWQFIPYLLQALRPLYGDWDA
DFWRNIEEQTTSSSQQLLAGLINQLHYCPHDLYLIVDDFHMINDAGVYEALGYLLKHAPA
ALHLIIGSRFHPSLSLSLLQAQDQLVEIYDRDLQFTLEETRNYFSQTIDVPLSNQHVQRL
LSATEGWIAGMKIASLSPELLNDPEHLLRNIRGGTRAIARYLKEVVLDPLPAEFFDFLVK
TSFLNRLNAGLCNRVTGRDDSEAILAWIERHNLFLSALDEQGCWFRYHPLLQETLRTILQ
QNNDINLKHLHELASHWFVEQRLWSEAVRHALAAGKPIHNPGQDGAGAQSLAEEGDIDTL
VSWMRHLPASTDPSRIDLQINLAWALAHYFRFDESRQLLDNLDQMVVNHRDDIAPNAWLK
LRVVRAICEAFAEKIPESLAIVEPLLAKVPCGDTWVDGLICNILSYCHVVNQRYTDALEV
QRHMPCPESPLDNLFVSVYRAFIIAQCHLGQGDLENAWGHAENALRQAERYTGPQSTSGA
TLAPLLAEMAYERKNLDSLNTLLADRLEFIDRFGPPDALSRCYTYLARQALNDDMPHEAE
RLLEHAQRLAVSRGWQRPQALLLAEQARVRLQRANYPGAEQLQRQLEQLAARATIDAENP
CQRAIAQYAIVSRSRLLLASGQAPQASLLLGELVTEQERRGDRLSAARLRTLWSLSLCNS
GENAAAVAALQPAQQLAAQQHLKRIFLDAGETLQPLLVRVRETSAASEGDALWPGKGSQS
EGKRIQHENLDVNLDLSERELQILQLIADGQMNKEIARSLTISTETVKWHIKNIYAKLKV
SSRTQAMSRALEMKLLD