Protein Info for BWI76_RS14125 in Klebsiella michiganensis M5al

Annotation: SDR family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 PF00106: adh_short" amino acids 50 to 239 (190 residues), 164.3 bits, see alignment E=3.7e-52 PF08659: KR" amino acids 53 to 216 (164 residues), 35.4 bits, see alignment E=1.6e-12 PF13561: adh_short_C2" amino acids 58 to 290 (233 residues), 191.1 bits, see alignment E=3.7e-60

Best Hits

Swiss-Prot: 59% identical to YHXD_BACSU: Uncharacterized oxidoreductase YhxD (yhxD) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 86% identity to eae:EAE_18800)

MetaCyc: 53% identical to NADP+-dependent aldehyde reductase (Escherichia coli K-12 substr. MG1655)
1.1.1.-

Predicted SEED Role

"Oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3R1 at UniProt or InterPro

Protein Sequence (294 amino acids)

>BWI76_RS14125 SDR family oxidoreductase (Klebsiella michiganensis M5al)
MTTGNNSTLHYPLPPFVEQPQQPPGLASEMKPLPDHGETSYIGSGKLVGKKALITGGDSG
IGRAVAIAFAREGADVAIGYLPEEESDAAAVIALIQAEGRKAVAIPGDIRVESFCDTLVE
KAVAELGGLDIVVNNAGRQQYCESVEELSTAAFDATFKTNVYAPFWITKAALRHLSEGAA
IINTSSVQAFKPSEILLDYAQTKACNVAFTKSLAKQLGPRGIRVNAVAPGPYWTPLQSSG
GQPQEKVQQFGEDTPLGRPGQPVEIAPLYVLLASDACSYASGQVWCSDGGTGVA