Protein Info for BWI76_RS14070 in Klebsiella michiganensis M5al

Annotation: ECF subfamily RNA polymerase sigma-24 subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 186 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 16 to 176 (161 residues), 78.7 bits, see alignment E=2e-26 PF04542: Sigma70_r2" amino acids 17 to 77 (61 residues), 32.6 bits, see alignment E=1.1e-11 PF07638: Sigma70_ECF" amino acids 61 to 161 (101 residues), 22.9 bits, see alignment E=1.5e-08 PF08281: Sigma70_r4_2" amino acids 120 to 169 (50 residues), 43.8 bits, see alignment E=3.2e-15 PF04545: Sigma70_r4" amino acids 125 to 173 (49 residues), 27.1 bits, see alignment E=5e-10

Best Hits

KEGG orthology group: None (inferred from 80% identity to ddc:Dd586_2067)

Predicted SEED Role

"RNA polymerase sigma-54 factor RpoN" in subsystem Flagellar motility or Flagellum or Transcription initiation, bacterial sigma factors

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3X7 at UniProt or InterPro

Protein Sequence (186 amino acids)

>BWI76_RS14070 ECF subfamily RNA polymerase sigma-24 subunit (Klebsiella michiganensis M5al)
MKNGTVAESRLVSALNACRSRLKAFIRGRTPLRDEADDILQEVTYQLIRVEQPVENIAAW
LFRAARNEMTDRARKKRELPLAGGFSEEEEGDFPEDELAETLFGVPQTPEDEYLKALLWE
ELNQALSELPPAQREAFEKTELQGYSYRELAEESGVSEQALLSRKHKAVLYLRTRLRSLY
DELLAG