Protein Info for BWI76_RS14060 in Klebsiella michiganensis M5al

Annotation: secretory lipase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF03583: LIP" amino acids 114 to 206 (93 residues), 55.1 bits, see alignment E=1.9e-18 PF12146: Hydrolase_4" amino acids 118 to 358 (241 residues), 29.9 bits, see alignment E=8.9e-11 PF12697: Abhydrolase_6" amino acids 122 to 362 (241 residues), 28.8 bits, see alignment E=5e-10 PF01738: DLH" amino acids 310 to 358 (49 residues), 21.6 bits, see alignment 3.7e-08

Best Hits

KEGG orthology group: None (inferred from 63% identity to pct:PC1_0393)

Predicted SEED Role

"putative exported lipase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3N7 at UniProt or InterPro

Protein Sequence (380 amino acids)

>BWI76_RS14060 secretory lipase (Klebsiella michiganensis M5al)
MTYSLSRKFLAATSALLLLSMSAVPASAAGDSTDAVSPLNAANGLSEAAKQYLLHYPSRS
GVDGKTAREDTAAVFIPFGATPEGGWPVVVWAHGTVGVENHCAPSLNPRSDRDKQYLNTW
LSLGYAVVAPDYAGLGSAGLHHYLNARGEAWSVLDGVRAALKQFPLKNELILVGQSQGAH
AAFASAGYQPEYAPELNVRATVLTGTPYFEKGTTAADVLPPAAGKAPTGGDPKIPYIFYI
YLSAADSNPQLNPADYFQDNALPLLKEASNLCITPLNDEVMKAGLNAANSLKPGIDSLLN
ASVGSMLYPTLKIDHPVFIGIGGADINVPTAMQKRFADAVKSAGTRAEVHIYAGLDHSGT
VNPSLRDSVPFLIKTLNDKR