Protein Info for BWI76_RS14020 in Klebsiella michiganensis M5al
Annotation: aspartate aminotransferase family protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 64% identical to DAT_HAEIN: Diaminobutyrate--2-oxoglutarate aminotransferase (dat) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
KEGG orthology group: K00836, diaminobutyrate-2-oxoglutarate transaminase [EC: 2.6.1.76] (inferred from 96% identity to kva:Kvar_2499)MetaCyc: 68% identical to diaminobutyrate--2-oxoglutarate transaminase monomer (Acinetobacter baumannii AYE)
Diaminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.76]
Predicted SEED Role
"Diaminobutyrate--2-oxoglutarate aminotransferase (EC 2.6.1.76)" (EC 2.6.1.76)
MetaCyc Pathways
- norspermidine biosynthesis (4/6 steps found)
- ectoine biosynthesis (3/5 steps found)
- superpathway of polyamine biosynthesis III (4/8 steps found)
- ectoine degradation (1/4 steps found)
- rhizobactin 1021 biosynthesis (2/7 steps found)
- baumannoferrin biosynthesis (2/11 steps found)
- pyoverdine I biosynthesis (2/11 steps found)
KEGG Metabolic Maps
Isozymes
No predicted isozymesUse Curated BLAST to search for 2.6.1.76
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A285B3M7 at UniProt or InterPro
Protein Sequence (461 amino acids)
>BWI76_RS14020 aspartate aminotransferase family protein (Klebsiella michiganensis M5al) MMTDKVRIDTLGADLLDANNDTFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDADNKQ YLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSLLPGEGK EYCLQFTGPSGADAVEAALKLAKKYTGRSSVISFSGGYHGMTHGALSVTGNLSPKAAVNG MMPEVQFMPYPHQYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG VNPAPVEWLQRIRKVTQEHGILLIIDEVQAGFARTGKFFAFEHAGIEPDIIVMSKAVGGG LPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTTLRHLKDNKIADKTAAQGEWLKGK LAEMQKRYPVIGHVRGLGLMIGIEIVKPNEAPDHMGCYPADGELSALLQKKCFEAGLILE RGGRHGCVLRLLPSLLISNAELEIFFDKFEQALLAAGVKPV