Protein Info for BWI76_RS13960 in Klebsiella michiganensis M5al

Annotation: urea ABC transporter periplasmic protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR03427: ABC transporter periplasmic binding protein, urea carboxylase region" amino acids 27 to 352 (326 residues), 537.2 bits, see alignment E=7.3e-166 PF09084: NMT1" amino acids 58 to 237 (180 residues), 40.4 bits, see alignment E=1.7e-14

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 94% identity to kpe:KPK_2621)

Predicted SEED Role

"Urea carboxylase-related ABC transporter, periplasmic substrate-binding protein" in subsystem Urea decomposition

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3L8 at UniProt or InterPro

Protein Sequence (352 amino acids)

>BWI76_RS13960 urea ABC transporter periplasmic protein (Klebsiella michiganensis M5al)
MKTPPLLRSLILSLALLASVPSFAAVKKEFNVCWTIYAGWMPWGTISNEKIIDKWASKYG
IKINIVQLNDYIESINQYTAGQFDGCTMTNMDALTIPAAGGVDTTALITGSYSDGNDGVV
LKGANKKLSDLKGMAVYLPELSVSHYLLVRGLEKAGLQEKDVKVVNTSDADIVSAFGTSG
VRAAVAWNPQLSVIKKTPQTTEVFSSSQVPGELIDMMVVNTQTLKDNPALGKALTGAWFE
MMTKMRAGDTEALNAMAADSGTDLAGYQAQLKTTHLFWTPADTLTFISSPELAKTMQRVA
QFSFDKGLLGEGAQSADFIGMTFPGGVTVGDTANSKLRFDDSYLKLAAAGKL