Protein Info for BWI76_RS13795 in Klebsiella michiganensis M5al

Annotation: ABC transporter substrate binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details TIGR04028: ABC transporter substrate binding protein, KPN_01854 family" amino acids 32 to 538 (507 residues), 876.8 bits, see alignment E=2.1e-268 PF00496: SBP_bac_5" amino acids 74 to 437 (364 residues), 244.9 bits, see alignment E=7.6e-77

Best Hits

KEGG orthology group: K02035, peptide/nickel transport system substrate-binding protein (inferred from 91% identity to kva:Kvar_2450)

Predicted SEED Role

"ABC-type dipeptide transport system, periplasmic component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3J8 at UniProt or InterPro

Protein Sequence (540 amino acids)

>BWI76_RS13795 ABC transporter substrate binding protein (Klebsiella michiganensis M5al)
MHTRFRLPALAALFFSGAFSAWAADAPVKGGTLIYLEQQPHTNLYPPAGGFYPNGGILNQ
ITDKLTWQNPETLQVEPWIAESWSVNADKTEYIFKIRPGVTFSDGTPLDANAVAKNFDTY
GLGNKARRLPVSEVINNYDRSEVIDPLTVKFYFKKPSPGFLQGTATIGSGLVSLSTLARN
FEELGDARHIIGSGPFTVKDEKPGRELTLVARKDYQWGPKSLAQQGPANLDGITYIVTPE
DGVRIGALLAGQADFIRQVQAYDEKQATDAGFKIYAAPTRGVNDSLSFRPDNPLVADLRV
RQALLHATDAKQVVETLFSANYPQATSVVASSAAGYVNLSDRLAFDPAKAKQLLDEAGWK
PAADGIRVKDGQRLALTVYESLPQPQNKEVLQLIAQQWRQVGVALAVKAGDAGSRTLDSL
DPLKTPLTVSEVGRADPDVVKSMFFPTNRDALLQKGGSSDKVQSFRDDKLNALLTAISAE
VEPQKRLQLTGDAQRYLLDNAYVIPIFEEPQVFAGAPWVKGVSFEAVGRPSFYGAWLEKH