Protein Info for BWI76_RS13635 in Klebsiella michiganensis M5al

Annotation: extracellular solute-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 322 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13531: SBP_bac_11" amino acids 29 to 275 (247 residues), 86.3 bits, see alignment E=5.6e-28 PF01547: SBP_bac_1" amino acids 36 to 272 (237 residues), 76.3 bits, see alignment E=8.8e-25 PF13416: SBP_bac_8" amino acids 43 to 288 (246 residues), 74.9 bits, see alignment E=2e-24 PF13343: SBP_bac_6" amino acids 74 to 291 (218 residues), 98.1 bits, see alignment E=1.2e-31

Best Hits

KEGG orthology group: K02012, iron(III) transport system substrate-binding protein (inferred from 88% identity to kva:Kvar_2423)

Predicted SEED Role

"Ferric iron ABC transporter, iron-binding protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3H2 at UniProt or InterPro

Protein Sequence (322 amino acids)

>BWI76_RS13635 extracellular solute-binding protein (Klebsiella michiganensis M5al)
MKAVMTVKKGAVLAMMLSATMISSAHALTVYTAGPGSLAKSLASGYEQKTGVKVNIFQAT
TGKVMARLEAEQANPQADVLISASWDTAEDLHHRGWLLPYQSANADKVPANLKSADYVAQ
GISALGIVWNSKSGTPEPKEWRDLTEAAFKNKVTTPDPALSGASLDLLIGLQNGMGDKAW
ALFDDLKNNGMVVSGPNAQAVTPVMQGAKAAVFGAVDYVSYGNIDQGESLKVIFPASGTV
IAPRPMMILKTSQHADDAKAFVDYVLSPEGQARVADAWLMPARSDVPAKRPLLNELKILP
TVSDGKSDRSAVLSRFNTLFAQ