Protein Info for BWI76_RS13605 in Klebsiella michiganensis M5al

Annotation: porin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF11471: Sugarporin_N" amino acids 26 to 56 (31 residues), 36.1 bits, see alignment (E = 6e-13) PF02264: LamB" amino acids 105 to 534 (430 residues), 317.1 bits, see alignment E=3.2e-98

Best Hits

Swiss-Prot: 48% identical to SCRY_KLEPN: Sucrose porin (scrY) from Klebsiella pneumoniae

KEGG orthology group: None (inferred from 86% identity to kpn:KPN_01892)

Predicted SEED Role

"Maltoporin (maltose/maltodextrin high-affinity receptor, phage lambda receptor protein)" in subsystem Maltose and Maltodextrin Utilization or Trehalose Uptake and Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3N2 at UniProt or InterPro

Protein Sequence (534 amino acids)

>BWI76_RS13605 porin (Klebsiella michiganensis M5al)
MRISLISAAVCCALFSAYGASAAPLSVEQRLAQLEARLNHAEQEAGEAKRQAQQAELRTS
AAEQRAAAAEKQVQTLSQRTDATEQKQQAADKQLAKTRLSDGFEFNAYARSGMLVNSHGK
GERGGPGISPASSLNGDAHVGRLGNEKDNYVELSFGKKMTFSDGSWAHFKTMLADGATNP
DPWVQDNDSHHLNVRQLYVEMGNFADFSGPFRNASIWAGKRFDRDNFDIHFTDSDIMFLG
GTGGGINDVNWNSALRGDYSVYARSFGDLGSDNYEDNDIQNLMFTANHFWNNWQLMTTAM
TAQGNDSLKDNTSTTGSYALRSDNTAKNGYYAMLAYHDKQRFYGLAPGVSESALQYGGGL
GAEARQPGSDGDLTENAKSLRFASYGILPLGKNWQLAPSVIAQHSEDRYRDGDRYDWATF
NLRVSQGITRNFALLYEASWQYMDLNPHGRTYRYDSGVHQYQAVSGDFYKLTFAPTFKVG
DVLDIKARPEIRFFVTWMNWDKNLDRYAINDDFGSKGFTAGGNWNFGVQTEIWF