Protein Info for BWI76_RS13390 in Klebsiella michiganensis M5al

Annotation: ubiquinol oxidase subunit II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 336 transmembrane" amino acids 7 to 34 (28 residues), see Phobius details amino acids 70 to 98 (29 residues), see Phobius details amino acids 118 to 143 (26 residues), see Phobius details amino acids 156 to 181 (26 residues), see Phobius details amino acids 193 to 214 (22 residues), see Phobius details amino acids 227 to 248 (22 residues), see Phobius details amino acids 258 to 281 (24 residues), see Phobius details amino acids 301 to 324 (24 residues), see Phobius details TIGR00203: cytochrome d ubiquinol oxidase, subunit II" amino acids 5 to 213 (209 residues), 133.6 bits, see alignment E=5.2e-43 PF02322: Cyt_bd_oxida_II" amino acids 5 to 325 (321 residues), 324.8 bits, see alignment E=3e-101

Best Hits

KEGG orthology group: None (inferred from 86% identity to eae:EAE_20165)

MetaCyc: 65% identical to cyanide insensitive ubiquinol oxidase subunit II (Pseudomonas putida KT2440)
RXN-6883 [EC: 1.10.3.11]

Predicted SEED Role

"putative Cytochrome bd2, subunit II" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.10.3.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3N9 at UniProt or InterPro

Protein Sequence (336 amino acids)

>BWI76_RS13390 ubiquinol oxidase subunit II (Klebsiella michiganensis M5al)
MGIDLSVIWFVIIVFATLMYIVMDGFDLGIGILFATTRDASDRDVMVNSVAPVWDGNETW
LVLGGAGLFGAFPLAYAVIIDALAIPLTLMLIGLIFRGVAFEFRFNATPSHRPFWDRAFM
GGSILATFTQGMVVGAVINGFAVSGRSFSGGMFDWLTPFTLFCGLGLCIAYALLGASWLV
MKSENALHHNMRVTARGLLLALLAAIVAISIWTPLAQPAIAERWFSLPNLFFLLPVPLLV
AAISAWLWRALRNSASHLLPFVLTLGLIFLGFSGLGISIWPHIIPPGITLWQAAAPPQSQ
GFMLVGALLILPVILGYTFWSYYVFRGKVQHGEGYH