Protein Info for BWI76_RS13170 in Klebsiella michiganensis M5al

Annotation: methyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 219 PF01596: Methyltransf_3" amino acids 20 to 205 (186 residues), 148.6 bits, see alignment E=3e-47 PF01135: PCMT" amino acids 47 to 146 (100 residues), 28.5 bits, see alignment E=2.6e-10 PF13847: Methyltransf_31" amino acids 56 to 170 (115 residues), 27.5 bits, see alignment E=4.7e-10 PF13578: Methyltransf_24" amino acids 61 to 164 (104 residues), 58.5 bits, see alignment E=2.3e-19

Best Hits

Swiss-Prot: 34% identical to Y1364_MYCA1: Putative O-methyltransferase MAV_1364 (MAV_1364) from Mycobacterium avium (strain 104)

KEGG orthology group: None (inferred from 85% identity to eae:EAE_20435)

Predicted SEED Role

"O-methyltransferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B3A7 at UniProt or InterPro

Protein Sequence (219 amino acids)

>BWI76_RS13170 methyltransferase (Klebsiella michiganensis M5al)
MQQQWSAVDNYLVEALIPNDPLLSQVLENNQRAGLPAIDVAANQGQFLALLVRMTGAKRI
LEIGTLGGYSTIWMARELPADGELLTLEADAHHAAVARENLRLAGVDDRVAVLEGPALTS
LEKLGDRPPFDLIFIDADKPNNPNYLRWALRYSRPGTVIVGDNVVRDGEVTNPDSADDRV
QGVRAFIDMMGSDPRLTVTALQTVGSKGWDGFTLAWVNA