Protein Info for BWI76_RS12625 in Klebsiella michiganensis M5al

Annotation: isoflavone reductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 309 PF05368: NmrA" amino acids 16 to 246 (231 residues), 58.2 bits, see alignment E=4.4e-20

Best Hits

KEGG orthology group: None (inferred from 74% identity to kpu:KP1_2428)

Predicted SEED Role

"FIG00553873: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2X0 at UniProt or InterPro

Protein Sequence (309 amino acids)

>BWI76_RS12625 isoflavone reductase (Klebsiella michiganensis M5al)
MEEHNVATDEKVLVLGSGQLGAAVLDSLVPAVIQRNGAISVIVSPGSWDARGKLRSAAHQ
KLADRGAEFIAVDVASSTPASLKDLFANFATIINCMGFVAGAGTQIKITRAALEARVKRY
FPWQFGVNYDAVGKGSGQPVWDEQYDVRTLLRAQTATEWVIISTGMFTSFLFEPAFDVVN
LSQNTLNALGRWDTQITVTSPADIGRLTTAIYLFEPRLINEVVFVAGETTSYGKLADTVE
RVTKRTFTRQVFTLPTLLEQLRMKPDDRMLRYRVAFARGDGMWWPMSETWNVQNNIPTQD
IESWLRSVI