Protein Info for BWI76_RS12440 in Klebsiella michiganensis M5al

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 463 transmembrane" amino acids 17 to 37 (21 residues), see Phobius details amino acids 53 to 74 (22 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 112 to 132 (21 residues), see Phobius details amino acids 142 to 163 (22 residues), see Phobius details amino acids 169 to 189 (21 residues), see Phobius details amino acids 203 to 222 (20 residues), see Phobius details amino acids 228 to 250 (23 residues), see Phobius details amino acids 271 to 296 (26 residues), see Phobius details amino acids 307 to 324 (18 residues), see Phobius details amino acids 336 to 356 (21 residues), see Phobius details amino acids 362 to 381 (20 residues), see Phobius details amino acids 410 to 431 (22 residues), see Phobius details amino acids 437 to 457 (21 residues), see Phobius details PF07690: MFS_1" amino acids 23 to 248 (226 residues), 102.8 bits, see alignment E=1e-33 amino acids 280 to 460 (181 residues), 55 bits, see alignment E=3.4e-19

Best Hits

Swiss-Prot: 54% identical to NORB_STAAR: Quinolone resistance protein NorB (norB) from Staphylococcus aureus (strain MRSA252)

KEGG orthology group: None (inferred from 88% identity to eae:EAE_20895)

Predicted SEED Role

"Zinc transport protein ZntB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2N3 at UniProt or InterPro

Protein Sequence (463 amino acids)

>BWI76_RS12440 MFS transporter (Klebsiella michiganensis M5al)
MSSVSLSEAQFVGTDRLLAGIVLSVLTFWLFAQSVINVVPAMKSSLDISLETLTLAVSLS
ALFSGCFVVASGGLADKFGRMRMTSFGLILSIVGSAMLVLSQGPALFLAGRVLQGLSAAC
IMPATLALIKTWYEGKARQRAVSFWVIGSWGGSGLCSFVGGAIATGLGWRWIFVFSIAVA
LAALLLLRGTPESRSASAQQHKLDISGLISLILALVLLNLFISKGHGWGWTSATSLAMLA
GALASGLFFIRNGQRKGDAALIDFALFRNRAYSAAVLSNFMLNGAIGTMMIASIWLQQGH
HLSPLESGMMTLGYLVTVLAMIRVGEKLLQRYGARLPMMIGPVFTAVGILLISCTFLDKS
TYIVTVFFSNVLFGFGLGCYATPSTDTAVVNAPENKVGVASGIYKMGSSLGGAMGIAVTA
SLFALFLPLGMASAAQYALWFNAALCLGSMALSALLLPRTGQS