Protein Info for BWI76_RS12100 in Klebsiella michiganensis M5al

Annotation: replication protein P

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 PF06992: Phage_lambda_P" amino acids 42 to 210 (169 residues), 204 bits, see alignment E=6.5e-65

Best Hits

Swiss-Prot: 61% identical to VRPP_LAMBD: Replication protein P (P) from Escherichia phage lambda

KEGG orthology group: None (inferred from 61% identity to eae:EAE_22425)

Predicted SEED Role

"Origin specific replication binding factor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (247 amino acids)

>BWI76_RS12100 replication protein P (Klebsiella michiganensis M5al)
MKSIAESMHNFDRKNFQRIAASMPEMRDAQSFAHQATKTAEVFNELFRQLLAVFPALANK
SAEDLNEMRRQWLLAFKENEITTVEQINAGMRVARKQEKPFMPSPGQFVAWCRSEEAVTV
GLPDASELVDMVYQYCRTRGQYPDAESYPWPEHKIEPITLKHKACYWMVTGLYTDMRAKG
LSDSELRRKASEELLRMVRRVNAGEVIPEPVKQIQKLGGRPLTQEQGLNKIAEIRAKFGL
GRGRNHG