Protein Info for BWI76_RS11960 in Klebsiella michiganensis M5al

Annotation: lipopolysaccharide assembly protein LapB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 389 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF13176: TPR_7" amino acids 71 to 99 (29 residues), 19.1 bits, see alignment (E = 5.8e-07) PF14559: TPR_19" amino acids 192 to 245 (54 residues), 28.7 bits, see alignment 7.5e-10 PF13181: TPR_8" amino acids 215 to 245 (31 residues), 14.2 bits, see alignment (E = 2.2e-05) PF13174: TPR_6" amino acids 219 to 243 (25 residues), 13.7 bits, see alignment (E = 4.6e-05) PF18073: Rubredoxin_2" amino acids 355 to 382 (28 residues), 46.7 bits, see alignment (E = 1.1e-15)

Best Hits

Swiss-Prot: 85% identical to LAPB_ECO57: Lipopolysaccharide assembly protein B (lapB) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 95% identity to kva:Kvar_3037)

Predicted SEED Role

"Heat shock (predicted periplasmic) protein YciM, precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2U9 at UniProt or InterPro

Protein Sequence (389 amino acids)

>BWI76_RS11960 lipopolysaccharide assembly protein LapB (Klebsiella michiganensis M5al)
MLELLFLLLPVAAAYGWYMGRRSAQQSKQDDASRLSRDYVTGVNFLLSNQQDKAVDLFLD
MLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQSLMESASLTYDQRLLAVQQLGRDYMAA
GLYDRAEGMFKQLVDETDFRLSALQQLLQIYQATSDWQSAIEVAERLVKLGKDKHRGEIA
NFWCELALQQMAGNDLDKAMALLRKGAAADRNSARVSIMMGRVWMEKGDYAKAVESLERV
IEQDKELVGETLEMLQTCYQQLGKIDEWEAFLRRCAEENTGATADLMLAQILEQREGAES
AQNYVTRQLERHPTMRVFHKLIDYHINEAEEGRAKESLGVLRHMVGEQVRSKPRYRCQKC
GFTAHTLYWHCPSCRSWSTIKPIRGLDGQ