Protein Info for BWI76_RS11450 in Klebsiella michiganensis M5al

Annotation: cyanate MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 394 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 51 to 72 (22 residues), see Phobius details amino acids 81 to 98 (18 residues), see Phobius details amino acids 104 to 126 (23 residues), see Phobius details amino acids 138 to 161 (24 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 212 to 234 (23 residues), see Phobius details amino acids 251 to 270 (20 residues), see Phobius details amino acids 278 to 297 (20 residues), see Phobius details amino acids 303 to 324 (22 residues), see Phobius details amino acids 334 to 355 (22 residues), see Phobius details amino acids 367 to 386 (20 residues), see Phobius details TIGR00896: cyanate transporter" amino acids 15 to 368 (354 residues), 446.4 bits, see alignment E=3.6e-138 PF07690: MFS_1" amino acids 20 to 348 (329 residues), 94.5 bits, see alignment E=3.2e-31

Best Hits

Swiss-Prot: 78% identical to NIMT_ECOLI: 2-nitroimidazole transporter (nimT) from Escherichia coli (strain K12)

KEGG orthology group: K03449, MFS transporter, CP family, cyanate transporter (inferred from 87% identity to kva:Kvar_3172)

MetaCyc: 78% identical to 2-nitroimidazole exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-273; TRANS-RXN0-596

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2J9 at UniProt or InterPro

Protein Sequence (394 amino acids)

>BWI76_RS11450 cyanate MFS transporter (Klebsiella michiganensis M5al)
MNSASPSADRRHLVLIAGILLIATTLRVAFTGAAPLLDAIRSEYGLTTAQTGLLTTLPLL
AFGLVSPLAAAVARRFGIERSLLLALILICLGIALRSLPVVTLLFIGTAIIGCGIALGNV
LLPGLIKRDFPQHVAKMTGAYSLTMGGAAALGSAMVVPLAFAGLSWRGALLMLMVFPLLA
LFVWLPQSRRQAAAPLTGSGAIHNRGIWRSALAWQVTLFLGINSLVYYVIIGWLPAILQS
IGYSEAQAGSLHGLLQLATAAPGLAIPLILHRLKDQRGIAVLVALMCAVSALGLWFLPGQ
AVLWTLIFGFGSGATMILGLTFIGLRASSAHQAAALSGMAQTVGYLLAACGPPVMGKIHD
ANGDWHIPLIAVALISIAMAVFGALAGRDREING