Protein Info for BWI76_RS11385 in Klebsiella michiganensis M5al

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 776 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF07660: STN" amino acids 59 to 108 (50 residues), 30.4 bits, see alignment 5.3e-11 TIGR01783: TonB-dependent siderophore receptor" amino acids 134 to 776 (643 residues), 512.9 bits, see alignment E=7.4e-158 PF07715: Plug" amino acids 134 to 246 (113 residues), 67.7 bits, see alignment E=2.5e-22 PF00593: TonB_dep_Rec" amino acids 329 to 743 (415 residues), 178.3 bits, see alignment E=1.1e-55 PF14905: OMP_b-brl_3" amino acids 438 to 757 (320 residues), 33.7 bits, see alignment E=4.6e-12

Best Hits

Swiss-Prot: 87% identical to FECA_ECOLI: Fe(3+) dicitrate transport protein FecA (fecA) from Escherichia coli (strain K12)

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 88% identity to cko:CKO_03833)

MetaCyc: 87% identical to ferric citrate outer membrane transporter (Escherichia coli K-12 substr. MG1655)
RXN0-1684

Predicted SEED Role

"Iron(III) dicitrate transport protein FecA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2A7 at UniProt or InterPro

Protein Sequence (776 amino acids)

>BWI76_RS11385 TonB-dependent siderophore receptor (Klebsiella michiganensis M5al)
MTPLRVLRKPMPLVMVIRLSLLPFAALAAAPAFAAAQFDIAAGDLDTVLNQYAARSGITL
SADASLTRGKHSPGLHGSFETEEGLHTLLNGSGLRLKPLGKNVWTLEPVPVSSESTLTVV
GDWLGDARENDVFEHAGARDVIRRGDFGKTGAATMREVLNRIPGVNAPENTGTGSHDLAM
NFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVSLGNMDAIDVVRGGGAVRYGP
QSVGGVVNFVTRAIPENFGIEGGVEGQLSPTSSQNNPKETHNFAIGGTAENGFGSALLYS
GTRGSDWRERSATRIDDVMLKSKYAPNEVHTFNSLLQYYDGEADMPGGLSRADYNADRWQ
STRPYDRFWGRRQLASLGYQFQPDAQHKFNIQGFYTHTLRSGYLEQGKRITLSPREYWVR
GIEPRYSQSFMIGPSAHEVGVGYRYVNESTHEMRYYTATTSGELPSSASPYDRDTRSGTE
AHAWYIDDRVDIGNWTITPGMRFEHIASYQDNALLGTRERVSYNAPLPALNVLYHLTDSW
NLYANTEGSFGTVQYSQIGKAVQSGNVEPEKARTWEVGTRYDDGALTAEMGLFLINFNNQ
YDSNQTNDTVTARGKTRHSGLEAQTRYSLGELSPALDNLSLYASYAYVNAEIREKGDTYG
NQVPFSPKHKGSFGVDYKPGSWTFNLNSDFQSSQFADNANTVAESADGSTGRIPGYMLWG
ARVAYDFGPQMANLNLALGVKNIFDHEYYTRSYDDNNKGLYAGQPRTLYLQGSMKF