Protein Info for BWI76_RS11355 in Klebsiella michiganensis M5al

Annotation: phosphodiesterase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 395 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details PF01966: HD" amino acids 26 to 129 (104 residues), 40.8 bits, see alignment E=3.9e-14 amino acids 221 to 341 (121 residues), 62.1 bits, see alignment E=9.4e-21 PF13487: HD_5" amino acids 210 to 365 (156 residues), 122.3 bits, see alignment E=2.9e-39

Best Hits

KEGG orthology group: None (inferred from 72% identity to kpn:KPN_01164)

Predicted SEED Role

"HD-GYP domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2H8 at UniProt or InterPro

Protein Sequence (395 amino acids)

>BWI76_RS11355 phosphodiesterase (Klebsiella michiganensis M5al)
MRIALKSALMLTSRVIQVINPELHLHMQRTALIALELAQASGLSRRQQQTIFCAALLHDI
GVLGDKRAFSSLNAIDNLNDPHQHRGAEMLAGLATLAPILPIIRDHHFSPNHRGSLEQHI
VYFADVFERQLPGDKSATTYQTDMSIDNFRALYQAIDPPLCQTLCQLAEKEHFWLHLNPG
HIQRMLEIIGPINDVYIDIDGLKDICLLIAKIVDTYSSFTASHSLKVGQISRDLAAYMSL
PDLECRKIEIAGYLHDIGKVYIPLAILEKQGELNDEELLQVREHSYMTGEILSTFSELGE
IINWAANHHEKLDGSGYPLHLNGDYLQLPDRIIAIADIFTALTEDRPYRPGMRRQQALQL
IESDVINGALDKDVYRILHQHAEALHAIITHTLPP