Protein Info for BWI76_RS11345 in Klebsiella michiganensis M5al

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 transmembrane" amino acids 215 to 235 (21 residues), see Phobius details PF00126: HTH_1" amino acids 10 to 69 (60 residues), 61.9 bits, see alignment E=4.5e-21 PF03466: LysR_substrate" amino acids 93 to 242 (150 residues), 85.2 bits, see alignment E=4.2e-28

Best Hits

KEGG orthology group: None (inferred from 78% identity to ebi:EbC_11650)

Predicted SEED Role

"Transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A285B2C7 at UniProt or InterPro

Protein Sequence (294 amino acids)

>BWI76_RS11345 LysR family transcriptional regulator (Klebsiella michiganensis M5al)
MNKLPLTFDLDALRSFVTGIECGSFAQAAGRLCRSTSAVSAQLKKLEQQCGTALVEKRGR
HLALTQNGEIIMGYARRLLALNDEAQRVLQGELLQGEIRIGMQEDFGESLMPGILGEFKR
HHPGMRIIARVDRNRALLNALNDNMLDMALLWQPESAQREGKPIGQSRLEWITHPQLDIA
ALLAEGKPLPLVMLDSPCLMRSRAIDCLDRANIAWQVVFISHSLSGIWAAVQAGLGITVR
TRIGMPGNLRVAGSLLPSPGNLGITLTHGQGNDGVHGARALLGQLMEDALLSVM